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This year, the campaign is once again aligned with the Disease Elimination Initiative, which aims to accelerate the elimination of more than 30 communicable diseases and related conditions by 2030, 11 of which are vaccine-preventable diseases. It also highlights vaccination as an essential strategy for achieving regional goals and avoiding critical setbacks, such as the loss of measles elimination re-verification in the Region.  This poses a real threat to public health, making it urgent to close immunity gaps and prevent outbreaks in all countries.